As the werewolves are in Zombietown, Zed tries to rally the wolves to help him win the election, but they do not see the point of changing who they are to fit in. They begin to suspect Addison is the Great Alpha, so they enroll at Seabrook High to get closer to her, which Addison welcomes with open arms. Prophecy states that a girl with white hair, called the Great Alpha, will show them where this moonstone is.

These moonstones are losing their power, so they need to find the moonstone in order to recharge their necklaces. They have moonstone necklaces which give them the werewolf abilities without them, they can die. Meanwhile, the local werewolves are getting sick. Zed realizes if he runs for president, he can change things for both the zombies and werewolves. This notably means that the zombies cannot go to prawn. When they get back to Seabrook, the whole town freaks out, and the mayor reinstates the anti-monster laws. Due to a road incident caused by Zed's prawnposal, the bus carrying the cheerleaders crashes into the nearby forbidden forest Addison and the cheer team see the werewolves and freak out. Zed plans to ask Addison to the prawn, while Addison works to become the new cheer captain when Bucky steps down to become president. In the present, time has passed since Seabrook and Zombietown settled their differences. In the earlier days of Seabrook, settlers fought off a group of werewolves from a moonstone that they have since kept hidden underground. But the arrival of a new group of outsiders - mysterious werewolves - threatens to shake up the newfound peace and causes a rift in Zed and Addison's budding romance.

The sequel picks up at Seabrook High, where, after a groundbreaking semester, Zed and Addison continue to steer both their school and community toward unity.

Zed from zombies 2